There are a lot of advantages to living in a large U.S. city. Exceptional job opportunities and access to cultural attractions entice many to move to a particular place. Living in a highly populated town, though, usually comes with a costly price tag. Housing expenses, food prices, transportation costs, and other budget concerns help determine whether you can afford to live where you'd like to relocate. Some of the more desirable and most expensive cities to live in the U.S. tend to be on the east and west coasts, with one or two exceptions.

01Boston

Boston is one of the country's most popular cities, with its unrivaled universities, top-notch medical centers, and iconic historical sites. Although not quite as expensive as New York, Boston is still above the national average when it comes to housing and food costs. Expect to spend over $1800 a month for a studio apartment and more than $2 million if you want to buy a home in the Back Bay area.